Researchers at the Icahn School of Medicine at Mount Sinai have characterized how cellular senescence—a biological process in ...

After three years of study, the researchers found that alpha-synuclein, a protein closely linked to Parkinson’s disease, forms an abnormal connection with an enzyme called ClpP. This enzyme normally ...

Cells manage a wide range of functions in their tiny package — growing, moving, housekeeping, and so on — and most of those functions require energy. But how do cells get this energy in the first ...

In the rapidly evolving field of drug discovery, single-cell analysis has become an invaluable tool for understanding cellular heterogeneity and molecular pathways. However, traditional single-cell ...

The mini review brings together emerging evidence showing that glial cells actively influence disease progression and ...

Microtubules are dynamic, tubular polymers composed of αβ-tubulin dimers that form an essential framework within eukaryotic cells. They orchestrate a wide range of cellular functions including ...

Precise methods for shredding or repairing and replacing specific cancer-causing proteins in a malignant cell, developed at ...

Single-cell analysis is a ubiquitous laboratory technique that allows researchers to probe the myriad biomolecular states of cells. Single-cell assays can reveal gene and protein expression patterns, ...

A new study reveals that age-related changes in the gut microbiota directly impair intestinal stem cell (ISC) function and that restoring a youthful microbial environment can reverse this decline.

Findings from the Living Brain Project reveal how senescence processes involved in early brain development may also shape brain aging ...

Stanford University-led researchers report that tumor cells hijack mitochondria from immune cells, reducing anti-tumor immune ...

The Immune Atlas identifies immune signatures in MM, enhancing outcome prediction and guiding personalized therapies by ...