Figure 1. A closed-circuit cooler. Photos courtesy of Evapco. It’s a common question during the early design phase of large mechanical systems: Is open- or closed-loop cooling equipment better suited ...

With open-loop therapies, insulin administration is manually controlled, while hybrid closed-loop systems automatically regulate insulin delivery. A study showed that hybrid closed-loop systems offer ...

Currently, one closed-loop system, the Medtronic MiniMed 670G, is in commercial use in the United States, but randomized trials are needed to assess its efficacy and safety. 8 Such a system, which ...