The design of a two-color microarray experiment can be considered as having three layers. Figure 1 shows an example of an experiment that compares the effects of two treatments—A and B—on ...

Amid growing concerns about the poor design of animal experiments and its implications for the translatability of experimental results, Michael F. W. Festing thinks it's time we do something about it.

Sound experimental design is of vital importance when conducting any scientific experiment. Choices made at the design stage have the potential to drastically impact the results of any study. A strong ...

Preclinical model systems are invaluable tools for drug discovery and development. But many complex diseases, such as nonalcoholic steatohepatitis (NASH), are difficult to recapitulate in the ...

The new experimental design was tried out on mice from different breeding lines, with several weeks between each 'mini-experiment'. In order to evaluate the reproducibility of the results in both ...

The design of experiments (DOE, DOX, or experimental design) is the design of any task that aims to describe and explain the variation of information under conditions that are hypothesized to reflect ...

Quantum designers: Florian Marquardt (left) and Leopoldo Sarra have shown how deep Bayesian experimental design can be applied to quantum many-body systems. (Courtesy: Leopoldo Sarra) As quantum ...