Edward Lyman, associate professor in the departments of physics and astronomy, as well as chemistry and biochemistry, was recently published in the journal Nature Chemical Biology. The article, “When ...

A recent review article highlights evolving MS-based methodologies that are reshaping ligand discovery and mechanistic characterization for membrane protein drug targets. LCGC International spoke to ...

Membrane proteins play an essential role in countless biological processes and are pivotal targets in drug discovery. However, their inherent amphipathic nature necessitates the development of ...

Cellular membrane proteins play many important roles throughout the body, including transporting substances in and out of the cell, transmitting signals, speeding up reactions and helping neighboring ...

LA JOLLA, CA—Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane’s challenging biochemical properties. Now, Scripps Research chemists have ...

Adaptor protein (AP) complexes play central roles in intracellular vesicular trafficking by coupling cargo selection to ...

A Scripps team has adapted advanced imaging and computation to measure cell membrane thickness inside intact animal and yeast ...

Researchers from the Heart Center of the University Medical Center Göttingen (UMG) led by Priv.-Doz. Dr. Sören Brandenburg have identified a protein that plays a central role in the heart's adaptation ...

Cancer cells have softer membranes than healthy cells. New nanoparticles exploit this physical difference to fuse selectively ...